Charlie (Liam Neeson) is a legendary undercover agent who has been involved in more drug busts than he cares to remember except that his instinct for danger cool composure and nerves of steel have failed him. In this his final assignment a number of larger-than-life characters are drawn together for a comic story of drug deals. The combination of a trigger-happy Mafia hitman and cocky Columbian drug barons leaves Charlie in too deep. In an attempt to pull off his last mission before he loses the plot completely Charlie seeks a hilariously funny self-help therapy group and the aid of sexy nurse Judy (Sandra Bullock) in this comical gangster movie.