A drunk lonely and shambolic hit man Julian Noble (Brosnan) is on the verge of a nervous breakdown. In search of some real human connection and friendship a chance encounter with straight-laced mild-mannered travelling salesman Danny Wright (Greg Kinnear) in Mexico City triggers a strange bond between the two. As fate brings them together and bound by an awkward friendship their very existence begins to take on a whole new meaning as their lives are altered forever....