Eddie Murphy stars as Dr Sherman Klump a kind ""calorically challenged"" genetics professor who longs to shed his 400-pound frame in order to win the heart of beautiful Jada Pinkett. So with one swig of his experimental fat-reducing serum Sherman becomes ""Buddy Love"" a fast-talking pumped-up plumped-down Don Juan. Can Sherman stop his buff alter ego before it's too late or will Buddy have the last laugh?